M-Class standard safety features: side curtain airbags, side-impact airbags, electronic stability system, four-wheel-disc antilock brakes, active front head restraints, and Pre-Safe, which can cinch the front seat belts and close the windows in case of a crash.
| Standard Specs and Dimensions |
| Four-wheel ABS brakes | Standard |
| 4 ABS channels | Standard |
| Brake assist | Standard |
| Four-wheel disc brakes | Standard |
| Front and rear ventilated disc brakes | Standard |
| Daytime running lights | Standard |
| Driver and passenger front-impact airbags | Standard |
| Seat-mounted driver and passenger side-impact airbags | Standard |
| Curtain 1st and 2nd row overhead airbag | Standard |
| Rear side-impact-impact airbag | Standard |
| Front passenger airbag occupancy sensor | Standard |
| Height adjustable front seatbelts | Standard |
| Front and rear seatbelt pre-tensioners | Standard |
| 3 point rear center seatbelt | Standard |
| Locking fuel flap included with power door locks | Standard |
| Side-impact bars | Standard |
| Remote activated perimeter/approach lights | Standard |
| Tailgate/rear door lock included with power door | Standard |
| Rear child safety locks | Standard |
| Ignition disable | Standard |
| Panic alarm | Standard |
| Tracker system | Standard |
| Stability control | Standard |
| ABS and driveline traction control | Standard |
| Manual adjustable front head restraints with tilt | Standard |
| Anti-whiplash front head restraints | Standard |
| 3 rear head restraints | Standard |
| First aid kit | Standard |
